Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.51 |
| ▸ | CA1 | P00915 | 9/20 | 0.51 |
| ▸ | CA2 | P00918 | 9/20 | 0.51 |
| ▸ | CA9 | Q16790 | 9/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6539243 | 0.85 | TP53 (0.56) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6132534 | 0.84 | TP53 (0.50) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL7323795 | 0.83 | CA12 (0.56) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL6538546 | 0.82 | MAPT (0.53) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6135226 | 0.81 | MAPT (0.43) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL7316392 | 0.81 | TP53 (0.47) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL7317504 | 0.81 | TP53 (0.50) | CA12CA1CA2CA9CA7 | |
| Trifluoroacetic Acid SCHEMBL6538606 | 0.80 | TP53 (0.47) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL7325659 | 0.80 | SIRT2 (0.46) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6134595 | 0.79 | CA12 (0.42) | CA12CA1CA2CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |