Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298274 | 1.00 | HPGD (0.37) | HPGDGAAL3MBTL1CTSSCTSL | |
| SCHEMBL7321106 | 0.80 | REN (0.43) | REN | |
| SCHEMBL7312408 | 0.80 | REN (0.43) | REN | |
| SCHEMBL968973 | 0.75 | CYP2D6 (0.42) | REN | |
| SCHEMBL968972 | 0.75 | CYP2D6 (0.42) | REN | |
| SCHEMBL7316735 | 0.75 | HPGD (0.49) | HPGDGAAPOLBHSD17B10SLC6A3 | |
| SCHEMBL7316081 | 0.75 | HPGD (0.49) | HPGDGAAPOLBHSD17B10SLC6A3 | |
| SCHEMBL1862727 | 0.74 | LTA4H (0.43) | CTSLMEN1KMT2ACTSBREN | |
| SCHEMBL7292991 | 0.74 | REN (0.43) | HPGDKMT2AREN | |
| SCHEMBL7429514 | 0.74 | REN (0.43) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |