Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316081 | 1.00 | HPGD (0.49) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL7359827 | 0.84 | KLK5 (0.55) | HPGDACE | |
| SCHEMBL10592904 | 0.81 | KLK5 (0.54) | SLC6A3ACE | |
| SCHEMBL7363045 | 0.77 | HPGD (0.45) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL5431141 | 0.76 | KDM4E (0.50) | HPGDKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL5431147 | 0.76 | KDM4E (0.50) | HPGDKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7298274 | 0.75 | HPGD (0.37) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL7317655 | 0.75 | HPGD (0.37) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL7276779 | 0.74 | LMNA (0.44) | HPGDLMNATDP1CYP1A2 | |
| SCHEMBL10590526 | 0.73 | SLC6A3 (0.42) | HPGDKMT2ALMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |