Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 6/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313463 | 0.91 | PDE4A (0.35) | ALDH1A1MEN1GAAKMT2AITGA4 | |
| SCHEMBL7311511 | 0.91 | ALDH1A1 (0.35) | ALDH1A1MEN1GAAKMT2APDE4A | |
| SCHEMBL7351300 | 0.91 | LCK (0.36) | ALDH1A1ITGA4ITGB7PDE4APDE4B | |
| SCHEMBL7320735 | 0.88 | PDE4A (0.43) | ALDH1A1ITGA4ITGB7PDE4APDE4B | |
| SCHEMBL7311535 | 0.81 | MAPT (0.37) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL7319179 | 0.81 | LCK (0.36) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL7311518 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MEN1GAAKMT2APDE4A | |
| SCHEMBL7314035 | 0.77 | LMNA (0.35) | ALDH1A1GAAKMT2APDE4APDE4B | |
| SCHEMBL7311435 | 0.76 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7307197 | 0.75 | PDE4A (0.36) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |