Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.77 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31442460 | 0.80 | UBE2T (0.70) | UBE2TF2PRSS1PRSS2PRSS3 | |
| SCHEMBL31442438 | 0.80 | UBE2T (0.70) | UBE2TF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL31442602 | 0.79 | UBE2T (0.68) | UBE2TF2PRSS1PRSS2PRSS3 | |
| SCHEMBL7316048 | 0.76 | F2 (0.75) | UBE2TF2PRSS1PRSS2PRSS3 | |
| SCHEMBL16661120 | 0.72 | UBE2T (0.58) | UBE2THRH3HPGDCRBN | |
| SCHEMBL16788248 | 0.71 | ITGB3 (0.58) | UBE2TF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1447393 | 0.70 | CNR2 (0.55) | ALDH1A1KMT2A | |
| SCHEMBL4677360 | 0.70 | GRIN2D (0.53) | UBE2TALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29475033 | 0.70 | UBE2T (0.71) | UBE2TALDH1A1HRH3KDM4EPOLB | |
| SCHEMBL3920532 | 0.70 | DHFR (0.48) | UBE2TALDH1A1HRH3KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843948-A | Piperazinophenyl- and piperazinophenyloxycarboxylic acid derivatives, and processes and intermediates for their preparation and pharmaceutical compositions comprising them | SOLVAY PHARMACEUTICALS GMBH (DE) | 1998-12-01 | — | — | US | disclosed |