SCHEMBL28876302

SCHEMBL28876302

O=C(O)C1(Cl)CC1c1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.44
KDM1A O60341 4/20 0.40
RCOR1 Q9UKL0 4/20 0.40
PTGS2 P35354 1/20 0.40
HSD11B1 P28845 3/20 0.39
LMNA P02545 3/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
BLM P54132 1/20 0.39
PPARA Q07869 1/20 0.39
SLC9A1 P19634 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
EPHX1 P07099 1/20 0.36
CCR2 P41597 1/20 0.35
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
BCL2L1 Q07817 1/20 0.33
BAD Q92934 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28317778 0.84 MAPK1 (0.45) LIG1KDM1ARCOR1PTGS2LMNA
SCHEMBL3866422 0.83 MAPK1 (0.47) KDM1AMAPK1CYP2C19
SCHEMBL28316732 0.82 LMNA (0.39) KDM1ALMNACYP2C9TSHRBLM
SCHEMBL28190260 0.81 CCR2 (0.36) KDM1ALMNACYP2C9TSHRBLM
Hydrochloric Acid SCHEMBL3605048 0.81 NPC1 (0.45) KDM1A
SCHEMBL28316797 0.80 KDM1A (0.46) KDM1ARCOR1HSD11B1TDP1CCR2
SCHEMBL7317859 0.78 HAO1 (0.44) CYP2C9BLMMEN1KMT2ATDP1
SCHEMBL28190259 0.77 CES2 (0.35) CES2CES1
SCHEMBL28268441 0.77 CA12 (0.43) CYP2C19
SCHEMBL14645495 0.76 LIG1 (0.45) LIG1KDM1ARCOR1PTGS2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072842-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2019-07-30 CN disclosed