Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518497 | 1.00 | LDHA (0.53) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL106531 | 1.00 | LDHA (0.53) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8143842 | 0.89 | SLC6A4 (0.50) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7317870 | 0.89 | SLC6A4 (0.50) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3729750 | 0.88 | ACACB (0.50) | LDHACYP1A2CYP2D6CYP2C19ACACB | |
| SCHEMBL2311151 | 0.88 | ACACB (0.50) | LDHACYP1A2CYP2D6CYP2C19ACACB | |
| SCHEMBL2311154 | 0.88 | ACACB (0.50) | LDHACYP1A2CYP2D6CYP2C19ACACB | |
| SCHEMBL16080173 | 0.88 | ACACB (0.50) | LDHACYP1A2CYP2D6CYP2C19ACACB | |
| Hydrochloric Acid SCHEMBL29398263 | 0.87 | ACACB (0.49) | LDHACYP1A2CYP2D6CYP2C19TPH1 | |
| Hydrochloric Acid SCHEMBL3745279 | 0.87 | ACACB (0.49) | LDHACYP1A2CYP2D6CYP2C19TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643393-B2 | Integrin antagonists | THE GENERAL HOSPITAL CORPORATION (US) | 2023-05-09 | — | — | US | disclosed |
| US-20220081398-A1 | Integrin Antagonists | THE GENERAL HOSPITAL CORPORATION | 2022-03-17 | — | — | US | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| EP-2258400-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS, INC. (US) | 2010-12-08 | — | — | EP | disclosed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |
| EP-0594588-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | Pfizer Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| WO-1991013054-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1991-09-05 | — | — | WO | disclosed |
| EP-0159396-B1 | CARBOXYALKYL PEPTIDE DERIVATIVES | G.D. Searle & Co. (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0185380-B1 | THIOL BASED COLLAGENASE INHIBITORS | G.D. Searle & Co. (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4681966-A | ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0185380-A2 | Thiol based collagenase inhibitors | G.D. Searle & Co. (US) | 1986-06-25 | — | — | EP | disclosed |
| US-4595700-A | Thiol based collagenase inhibitors | G. D. SEARLE & CO. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4568666-A | COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS | G. D. SEARLE & CO. (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0159396-A2 | Carboxyalkyl peptide derivatives | G.D. Searle & Co. (US) | 1985-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081398-A1 | Integrin Antagonists | ITGA2B, ITGA2, ITGB2 | LDHA 3997/4885SLC6A4 4570/4885CYP1A2 4735/4885 |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | TLR2, TLR4, TLR1 | LDHA 2536/4885SLC6A4 3863/4885CYP1A2 3337/4885 |
| US-11643393-B2 | Integrin antagonists | ITGA2B, ITGA2, ITGB2 | LDHA 3997/4885SLC6A4 4570/4885CYP1A2 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.