Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747465 | 0.81 | ADORA1 (0.37) | ADORA1ADORA2A | |
| SCHEMBL14431623 | 0.81 | ADORA1 (0.37) | ADORA1ADORA2A | |
| SCHEMBL2179685 | 0.80 | AURKA (0.30) | — | |
| SCHEMBL14536745 | 0.78 | AURKA (0.30) | — | |
| SCHEMBL19747597 | 0.78 | GABRA1 (0.30) | — | |
| SCHEMBL25397536 | 0.76 | ADORA1 (0.37) | ADORA1ADORA2A | |
| SCHEMBL8240075 | 0.75 | ADORA2A (0.55) | ADORA1ADORA2A | |
| SCHEMBL7319030 | 0.73 | IKBKB (0.43) | — | |
| SCHEMBL8240149 | 0.72 | AURKA (0.41) | ADORA2A | |
| SCHEMBL5401158 | 0.71 | TLR7 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028605-A | Antispasmodic, bronchodilators, uterine relaxants, cardiac analeptics, neurosedatives | L'UNIVERSITE DE MONTPELLIER I (FR) | 1991-07-02 | — | — | US | disclosed |
| EP-0348392-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Université Montpellier I (FR) | 1990-01-03 | — | — | EP | disclosed |
| WO-1988004298-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-06-16 | — | — | WO | disclosed |