Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 7/20 | 0.41 |
| ▸ | MMP13 | P45452 | 7/20 | 0.41 |
| ▸ | MMP8 | P22894 | 6/20 | 0.41 |
| ▸ | MMP12 | P39900 | 6/20 | 0.41 |
| ▸ | MMP14 | P50281 | 6/20 | 0.41 |
| ▸ | MMP16 | P51512 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316532 | 0.91 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7317410 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7313804 | 0.88 | ALDH1A1 (0.45) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7321207 | 0.88 | ALDH1A1 (0.45) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7322302 | 0.88 | MMP9 (0.42) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7323686 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7354908 | 0.87 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7316252 | 0.86 | HSP90AA1 (0.46) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7315550 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL7322659 | 0.83 | MMP2 (0.47) | ALDH1A1POLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |