Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.71 |
| ▸ | ROCK1 | Q13464 | 11/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.69 |
| ▸ | PRKCG | P05129 | 4/20 | 0.69 |
| ▸ | PRKCB | P05771 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | PRKCA | P17252 | 4/20 | 0.69 |
| ▸ | PRKCH | P24723 | 4/20 | 0.69 |
| ▸ | PRKCI | P41743 | 4/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.69 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.69 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.69 |
| ▸ | PRKACA | P17612 | 3/20 | 0.69 |
| ▸ | PRKACG | P22612 | 3/20 | 0.69 |
| ▸ | PRKACB | P22694 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326564 | 0.93 | ROCK2 (0.65) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL4729640 | 0.87 | ROCK2 (0.74) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL7315524 | 0.85 | CYP3A4 (0.62) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL10988523 | 0.85 | ROCK2 (0.79) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL4729716 | 0.84 | ROCK2 (0.70) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL19543804 | 0.84 | ROCK2 (0.83) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL10985139 | 0.84 | ROCK2 (0.77) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL29770053 | 0.84 | ROCK2 (0.77) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL6916059 | 0.84 | ROCK2 (0.77) | ROCK2ROCK1PRKD3PRKCGPRKCB | |
| SCHEMBL26584304 | 0.84 | ROCK2 (0.77) | ROCK2ROCK1PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4798897-A | (AMINOALKYL)AMINOSULFONYL-SUBSTITUTED CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |