Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 5/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.61 |
| ▸ | PRKCB | P05771 | 4/20 | 0.61 |
| ▸ | PRKCA | P17252 | 4/20 | 0.61 |
| ▸ | PRKCH | P24723 | 4/20 | 0.61 |
| ▸ | PRKCI | P41743 | 4/20 | 0.61 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.61 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.61 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | PRKACA | P17612 | 6/20 | 0.60 |
| ▸ | PRKACG | P22612 | 5/20 | 0.60 |
| ▸ | PRKACB | P22694 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323569 | 0.83 | PRKCG (0.54) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9832298 | 0.80 | ALDH1A1 (0.41) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7318215 | 0.80 | FLT3 (0.47) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9541290 | 0.80 | PRKCG (0.86) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7319611 | 0.78 | P2RX7 (0.43) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9544846 | 0.78 | PRKACA (0.80) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL1272378 | 0.77 | PRKCG (1.00) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL30884868 | 0.77 | PRKCG (1.00) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7326901 | 0.77 | CYP3A4 (0.44) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7312125 | 0.76 | PRKACA (0.78) | PRKCGPRKCZPRKCDPRKD3PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |