Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.49 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12871476 | 0.87 | SIRT2 (0.54) | — | |
| SCHEMBL16059278 | 0.84 | ATM (0.53) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL22370935 | 0.84 | ATM (0.53) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL16059281 | 0.84 | ATM (0.53) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL9383829 | 0.81 | CTSS (0.58) | SMN1; SMN2LMNACTSSCTSLCTSK | |
| SCHEMBL2723154 | 0.81 | SYK (0.71) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL2725000 | 0.81 | SYK (0.71) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL2723152 | 0.81 | SYK (0.71) | CTSSCTSLCTSKSYKCTSB | |
| SCHEMBL30016306 | 0.81 | CTSL (0.55) | RAB9ALMNACTSSCTSLCTSK | |
| SCHEMBL25879987 | 0.80 | ALDH1A1 (0.57) | LMNACTSSCTSLCTSKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |