Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331934 | 0.90 | OPRK1 (0.49) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL7332842 | 0.88 | CCKBR (0.47) | PDE4DHTR2BOPRK1LMNAKCNH2 | |
| SCHEMBL7320833 | 0.84 | OPRK1 (0.66) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL25409864 | 0.82 | OPRK1 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL31366637 | 0.82 | OPRK1 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL25409870 | 0.82 | OPRK1 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL25408967 | 0.79 | HDAC3 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL31366547 | 0.79 | HDAC3 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL25408970 | 0.79 | HDAC3 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A | |
| SCHEMBL25408963 | 0.79 | HDAC3 (0.52) | PDE4DHTR2BOPRK1LMNAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4388313-A | Novel 3-hydroxy-1,4-benzodiazepine-2-ones and process for the preparation thereof | GEROT-PHARMAZEUTIKA GESELLSCHAFT M.B.H. (AT) | 1983-06-14 | — | — | US | disclosed |