Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319307 | 0.80 | MMEL1 (0.44) | MMEL1L3MBTL1TLR2 | |
| SCHEMBL7320387 | 0.80 | MMEL1 (0.44) | MMEL1L3MBTL1TLR2 | |
| SCHEMBL7320395 | 0.79 | MMEL1 (0.44) | MMEL1TLR2 | |
| SCHEMBL7349076 | 0.79 | MMEL1 (0.44) | MMEL1TLR2 | |
| SCHEMBL7321260 | 0.75 | HDAC3 (0.38) | TLR2 | |
| SCHEMBL7322732 | 0.74 | TLR2 (0.38) | TLR2 | |
| SCHEMBL7314444 | 0.74 | TLR2 (0.39) | L3MBTL1TLR2 | |
| SCHEMBL7309636 | 0.73 | TLR2 (0.41) | L3MBTL1TLR2 | |
| SCHEMBL7321253 | 0.73 | L3MBTL1 (0.39) | MMEL1L3MBTL1TLR2 | |
| SCHEMBL7313712 | 0.72 | MMEL1 (0.53) | MMEL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |