SCHEMBL73194

SCHEMBL73194

O=C(Cl)c1ccnc(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.45
TAS1R1 Q7RTX1 2/20 0.45
TAS1R2 Q8TE23 2/20 0.45
RECQL P46063 1/20 0.45
SMARCA2 P51531 5/20 0.44
SMARCA4 P51532 4/20 0.44
PROKR1 Q8TCW9 1/20 0.42
KDM4E B2RXH2 1/20 0.41
KDM6B O15054 1/20 0.41
TET3 O43151 1/20 0.41
KDM4A O75164 1/20 0.41
BBOX1 O75936 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KDM5A P29375 1/20 0.41
KDM5C P41229 1/20 0.41
ASPH Q12797 1/20 0.41
KDM4D Q6B0I6 1/20 0.41
TET2 Q6N021 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6066419 0.98 TAS1R3 (0.44) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL27623752 0.84 RECQL (0.47) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL9446705 0.83 CYP11B1 (0.46) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL14204663 0.83 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL40123 0.83 KDM4C (0.61) TAS1R3TAS1R1TAS1R2RECQLKDM4E
SCHEMBL31547893 0.81 KDM4C (0.59) TAS1R3TAS1R1TAS1R2RECQLKDM4E
SCHEMBL29640105 0.81 SMARCA2 (0.49) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL1569241 0.81 CCNC (0.50) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL7842106 0.81 RECQL (0.48) TAS1R3TAS1R1TAS1R2RECQLSMARCA2
SCHEMBL29642415 0.81 CCNC (0.50) TAS1R3TAS1R1TAS1R2RECQLSMARCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108977192-A A kind of surface ligand is the preparation method of the quantum dot of deprotonation amine TCL集团股份有限公司 2018-12-11 CN claimed
JP-62265265-A None JP disclosed
JP-2229161-A None JP disclosed
JP-63275566-A None JP disclosed
JP-63301868-A None JP disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
EP-3609888-B1 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF LILLY CO ELI (US) 2025-08-27 EP disclosed
EP-4596041-A2 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF Organovo, Inc. (US) 2025-08-06 EP disclosed
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-13 US disclosed
CN-110637015-B Fanisole X receptor agonist and application thereof 奥加诺沃公司 2024-04-02 CN disclosed
JP-S63301868-A N-(2-CHLOROISONICOTINOYL)AMINO ACID DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPRISING SAID DERIVATIVE AS ACTIVE INGREDIENT NIPPON KAYAKU CO LTD 1988-12-08 JP disclosed
JP-S63275566-A N-(2-CHLOROISONICOTINOYL)AMINO ACID DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT NIPPON KAYAKU CO LTD 1988-11-14 JP disclosed
US-4736037-A 2-halo-aryl-pyridinemethanols with analgesic or antiinflammatory activity LACER, S.A. (ES) 1988-04-05 US disclosed
EP-0246507-A1 N-cyanoalkylisonicotinamide derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-11-25 EP disclosed
JP-S62265265-A N-CYANOALKYLISONICOTINIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT NIPPON KAYAKU CO LTD 1987-11-18 JP disclosed
US-4690934-A N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-09-01 US disclosed
US-4614833-A 2-halo-pyridines LACER, S.A. (ES) 1986-09-30 US disclosed
US-4514408-A INHIBITORS OF GASTRIC SECRETION SANOFI (FR) 1985-04-30 US disclosed
EP-0032516-B1 NEW 2-HALO-PYRIDINES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS LACER, S.A. (ES) 1984-05-02 EP disclosed
EP-0032516-A1 New 2-halo-pyridines, their production and pharmaceutical compositions LACER, S.A. (ES) 1981-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF CRBN, CRKL, ERBB3 TAS1R3 3062/4885TAS1R1 3288/4885TAS1R2 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.