Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73194 | 0.83 | TAS1R3 (0.45) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL6066419 | 0.82 | TAS1R3 (0.44) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27623752 | 0.81 | RECQL (0.47) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5197732 | 0.81 | CES2 (0.59) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4784283 | 0.79 | CES2 (0.47) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14204663 | 0.79 | TAS1R3 (0.45) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL40123 | 0.79 | KDM4C (0.61) | TAS1R3TAS1R1TAS1R2RECQLKDM4E | |
| SCHEMBL10080304 | 0.78 | CES1 (0.55) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7842106 | 0.78 | RECQL (0.48) | CYP11B1CYP11B2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1569241 | 0.78 | CCNC (0.50) | TAS1R3TAS1R1TAS1R2RECQLSMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216170-A | Promoters of livestock; treatment of obesity | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5028617-A | Heteroarylethanol-pyridylalkylamines for controlling animal growth | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |