Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266830 | 0.90 | ACE (0.51) | ANPEPERAP2ERAP1SLC6A2SLC6A4 | |
| SCHEMBL12249323 | 0.90 | ACE (0.51) | ANPEPERAP2ERAP1SLC6A2SLC6A4 | |
| SCHEMBL27264418 | 0.88 | SLC6A3 (0.53) | SLC6A2SLC6A4SLC6A3CYP3A4CYP1A2 | |
| SCHEMBL7266310 | 0.80 | ACE (0.47) | ANPEPERAP2ERAP1ACECYP3A4 | |
| SCHEMBL7279393 | 0.80 | ACE (0.45) | SLC6A3ACESMN1; SMN2EPHX1 | |
| SCHEMBL29276444 | 0.77 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3ACECYP3A4 | |
| SCHEMBL7266299 | 0.76 | EPHX1 (0.54) | ANPEPSLC6A2SLC6A4SLC6A3ACE | |
| SCHEMBL7266787 | 0.75 | SIGMAR1 (0.48) | ACECYP1A2GPR52RAB9A | |
| SCHEMBL7319593 | 0.74 | ANPEP (0.46) | ANPEPERAP2ERAP1SLC6A2SLC6A4 | |
| SCHEMBL1546515 | 0.74 | TAAR1 (0.46) | SLC6A2SLC6A4SLC6A3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |