Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319642 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7319626 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2ANPSR1KDM4E | |
| SCHEMBL7328791 | 0.77 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7324184 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7328061 | 0.74 | TP53 (0.43) | ALDH1A1L3MBTL1MAPK1LMNAPOLB | |
| SCHEMBL7331811 | 0.73 | SNCA (0.54) | ALDH1A1L3MBTL1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7361622 | 0.73 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPK1LMNAKMT2A | |
| SCHEMBL7327266 | 0.73 | MEN1 (0.50) | ALDH1A1SMN1; SMN2LMNAPOLBKMT2A | |
| SCHEMBL7292395 | 0.73 | — | — | |
| SCHEMBL9210396 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AHTTMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |