Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210401 | 0.84 | CES2 (0.46) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL248344 | 0.82 | NPSR1 (0.44) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL248343 | 0.82 | NPSR1 (0.44) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL2080613 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL7292395 | 0.77 | — | — | |
| SCHEMBL7319626 | 0.75 | ALDH1A1 (0.48) | ALDH1A1NPSR1MEN1KMT2AKDM4E | |
| SCHEMBL7319639 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL7328791 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL1304855 | 0.73 | STAT3 (0.45) | ALDH1A1NPSR1MEN1KMT2ACTSD | |
| SCHEMBL7324184 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368652-B1 | Imidazoquinoxalines and their preparation | NOVO NORDISK AS (DK) | 1995-03-01 | — | — | EP | disclosed |
| US-4999353-A | Chemical process for the preparation of imidazo-quinoxalines and intermediates for use in the process | NOVO NORDISK A/S (DK) | 1991-03-12 | — | — | US | disclosed |
| EP-0368652-A1 | Imidazoquinoxalines and their preparation | NOVO NORDISK A/S (DK) | 1990-05-16 | — | — | EP | disclosed |