Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7319896 | 0.99 | THRA (0.45) | THRATHRBBCHE | |
| SCHEMBL7316596 | 0.85 | BCHE (0.47) | THRATHRBBCHEHRH3 | |
| Hydrochloric Acid SCHEMBL7317679 | 0.84 | PKM (0.46) | THRATHRBBCHEHRH3 | |
| SCHEMBL7319679 | 0.83 | ALOX15 (0.35) | — | |
| SCHEMBL7677869 | 0.82 | NPC1 (0.58) | THRATHRBBCHEHRH3 | |
| Hydrochloric Acid SCHEMBL7319888 | 0.82 | ALOX15 (0.35) | — | |
| SCHEMBL7680783 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL7678308 | 0.80 | ADORA2A (0.56) | BCHEHRH3 | |
| SCHEMBL7680849 | 0.78 | HRH3 (0.54) | THRATHRBBCHEHRH3 | |
| SCHEMBL7680444 | 0.76 | HRH3 (0.54) | THRATHRBBCHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |