Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.65 |
| ▸ | LPAR1 | Q92633 | 16/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 16/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133651 | 0.83 | PARP10 (0.73) | PARP10LPAR1LPAR5 | |
| SCHEMBL9762139 | 0.82 | PARP10 (0.71) | PARP10LPAR1LPAR5FAAH | |
| SCHEMBL1162822 | 0.81 | PARP10 (0.60) | PARP10 | |
| SCHEMBL3022362 | 0.79 | PARP10 (1.00) | PARP10LPAR1LPAR5 | |
| SCHEMBL9762806 | 0.79 | PARP10 (0.71) | PARP10LPAR1LPAR5FAAH | |
| SCHEMBL11795042 | 0.79 | PARP10 (0.61) | PARP10LPAR1LPAR5 | |
| SCHEMBL30289632 | 0.79 | PARP10 (1.00) | PARP10LPAR1LPAR5 | |
| SCHEMBL10437240 | 0.78 | PARP10 (0.65) | PARP10LPAR1LPAR5FAAH | |
| SCHEMBL6293051 | 0.77 | PARP10 (0.66) | PARP10LPAR1LPAR5FAAHFFAR1 | |
| SCHEMBL9761680 | 0.76 | PARP10 (0.62) | PARP10LPAR1LPAR5FAAHCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304931-A | ANTIINFLAMMATORY AGENTS | THE BOOTS COMPANY LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
| US-4188491-A | PREPARING 2-(4-BIPHENYLYL)PROPIONIC ACIDS BY REACTING BIPHENYLYLMAGNESIUM BROMIDES WITH SODIUM PYRUVATE, ACIDIFYING | THE BOOTS COMPANY LIMITED (GB) | 1980-02-12 | — | — | US | disclosed |