Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299899 | 0.76 | TSHR (0.45) | TSHRKMT2ATHRBALDH1A1POLB | |
| Bromide SCHEMBL10413107 | 0.75 | TSHR (0.44) | TSHRKMT2ATHRBALDH1A1POLB | |
| SCHEMBL762893 | 0.73 | KMT2A (0.56) | TSHRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL28957583 | 0.72 | MEN1 (0.47) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL25399818 | 0.71 | ALDH1A1 (0.43) | TSHRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL25399680 | 0.69 | SMN1; SMN2 (0.45) | TSHRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL25406586 | 0.66 | TSHR (0.43) | TSHRKMT2ATHRBALDH1A1POLB | |
| SCHEMBL25397933 | 0.65 | SMN1; SMN2 (0.42) | TSHRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL11628529 | 0.64 | LTB4R (0.45) | LMNAMAPT | |
| SCHEMBL25400526 | 0.64 | SMN1; SMN2 (0.46) | TSHRKMT2ATHRBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-B1 | BENZIMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4925854-A | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |