Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 5/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309951 | 0.91 | REN (0.35) | CTSSCTSBCTSKCTSLREN | |
| SCHEMBL7319388 | 0.87 | REN (0.39) | CTSSCTSBCTSKCTSLREN | |
| SCHEMBL7320027 | 0.86 | CTSS (0.34) | CTSSCTSBCTSKCTSLREN | |
| SCHEMBL7309957 | 0.84 | CTSB (0.34) | CTSSCTSBCTSKCTSLREN | |
| SCHEMBL7320947 | 0.84 | — | — | |
| SCHEMBL7323390 | 0.83 | REN (0.32) | REN | |
| SCHEMBL7316972 | 0.83 | REN (0.30) | REN | |
| SCHEMBL7406580 | 0.83 | REN (0.42) | CTSSCTSBCTSLREN | |
| SCHEMBL7326352 | 0.82 | REN (0.31) | CTSSCTSBCTSKREN | |
| SCHEMBL7323447 | 0.81 | REN (0.39) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231919-B1 | N-HETEROCYCLIC ALCOHOL RENIN INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1993-01-20 | — | — | EP | disclosed |