Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668298 | 0.86 | PTGS1 (0.56) | PTGS1PTGS2MAPTPOLBTDP1 | |
| SCHEMBL7323109 | 0.84 | PTGS2 (0.50) | PTGS1PTGS2CARM1 | |
| SCHEMBL7318608 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2MAPTPOLBTDP1 | |
| SCHEMBL7318838 | 0.77 | PTGS1 (0.64) | PTGS1PTGS2MAPTPOLBTDP1 | |
| SCHEMBL7242652 | 0.77 | PTGS1 (0.60) | PTGS1PTGS2LMNAMAPTPOLB | |
| SCHEMBL7323201 | 0.77 | PTGS1 (0.60) | PTGS1PTGS2MAPTPOLBTDP1 | |
| SCHEMBL14887386 | 0.75 | MAPT (0.67) | PTGS1PTGS2LMNAMAPTPOLB | |
| SCHEMBL24133713 | 0.73 | NPC1 (0.48) | CARM1POLB | |
| SCHEMBL5212572 | 0.73 | PTGS1 (0.66) | PTGS1PTGS2MAPTPOLB | |
| SCHEMBL29766620 | 0.73 | CARM1 (0.40) | MAPTCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | PTGS1 197/4885PTGS2 158/4885LMNA 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.