Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320128 | 0.84 | PTGS1 (0.52) | PTGS2CARM1PTGS1 | |
| SCHEMBL7315273 | 0.81 | PTGS2 (0.51) | PTGS2CARM1PTGS1F10KLKB1 | |
| SCHEMBL24133713 | 0.77 | NPC1 (0.48) | CARM1 | |
| SCHEMBL29766620 | 0.74 | CARM1 (0.40) | CARM1F10KLKB1 | |
| SCHEMBL25897550 | 0.74 | CARM1 (0.40) | CARM1F10KLKB1 | |
| SCHEMBL7326690 | 0.72 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7234275 | 0.72 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL1670472 | 0.72 | GRN (0.56) | PTGS2CARM1PTGS1F10KLKB1 | |
| SCHEMBL1096199 | 0.71 | PTGS2 (0.61) | PTGS2PTGS1F10KLKB1 | |
| SCHEMBL14887387 | 0.70 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
| EP-1068187-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051580-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | PTGS2 158/4885CARM1 3375/4885PTGS1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.