Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315645 | 0.87 | L3MBTL1 (0.53) | TLR8L3MBTL1MGLLMAPTALDH1A1 | |
| SCHEMBL7334034 | 0.85 | TLR8 (0.55) | TLR8L3MBTL1MGLLMAPTALDH1A1 | |
| SCHEMBL27645962 | 0.82 | L3MBTL1 (0.55) | TLR8L3MBTL1MGLLMAPTALDH1A1 | |
| SCHEMBL7318801 | 0.79 | L3MBTL1 (0.53) | TLR8L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL7326808 | 0.79 | TLR8 (0.48) | TLR8MGLLGAAMAPTALDH1A1 | |
| SCHEMBL7314668 | 0.79 | TLR8 (0.48) | TLR8L3MBTL1MGLLGAAMAPT | |
| SCHEMBL24842016 | 0.77 | L3MBTL1 (0.45) | TLR8L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL7338762 | 0.74 | GAA (0.72) | L3MBTL1MGLLGAAMAPTALDH1A1 | |
| SCHEMBL6538620 | 0.74 | CYP4A11 (0.63) | GAAMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL21942690 | 0.74 | L3MBTL1 (0.55) | TLR8L3MBTL1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |