Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323285 | 0.88 | NPC1 (0.49) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7334034 | 0.88 | TLR8 (0.55) | TLR8SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7326808 | 0.83 | TLR8 (0.48) | TLR8SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL8090537 | 0.82 | HDAC3 (0.48) | SMN1; SMN2MAPTNPC1RAB9AHSD17B10 | |
| SCHEMBL7315645 | 0.80 | L3MBTL1 (0.53) | TLR8SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL7320147 | 0.79 | TLR8 (0.50) | TLR8POLBSMN1; SMN2MAPTKDM4E | |
| SCHEMBL7340342 | 0.78 | NPC1 (0.59) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7332034 | 0.78 | NPC1 (0.59) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7316044 | 0.77 | RARB (0.59) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7319130 | 0.77 | RARB (0.59) | POLBSMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |