Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344986 | 0.91 | LMNA (0.48) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7307978 | 0.83 | LMNA (0.49) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7313188 | 0.83 | LMNA (0.52) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7307893 | 0.82 | LMNA (0.43) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7306695 | 0.77 | PDE3B (0.47) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7319522 | 0.75 | MAOB (0.47) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7318725 | 0.75 | LMNA (0.54) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7316362 | 0.74 | LMNA (0.44) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7308032 | 0.73 | LMNA (0.51) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL10376795 | 0.73 | SIRT5 (0.44) | LMNAMAPK1THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |