Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308032 | 0.91 | LMNA (0.51) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL10376795 | 0.91 | SIRT5 (0.44) | LMNAMAPK1ALDH1A1SIRT5SMN1; SMN2 | |
| SCHEMBL10374480 | 0.90 | SIRT5 (0.43) | LMNAMAPK1ALDH1A1SIRT5SMN1; SMN2 | |
| SCHEMBL7316362 | 0.90 | LMNA (0.44) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL10377100 | 0.87 | LMNA (0.47) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL10374705 | 0.87 | THRA (0.44) | LMNAMAPK1SIRT5THRATHRB | |
| SCHEMBL10374589 | 0.86 | RAB9A (0.45) | LMNAMAPK1NPC1ALDH1A1SIRT5 | |
| SCHEMBL10375783 | 0.86 | MAPT (0.41) | LMNAMAPK1ALDH1A1SIRT5SMN1; SMN2 | |
| SCHEMBL10753639 | 0.86 | LMNA (0.47) | LMNAMAPK1NPC1ALOX15TSHR | |
| SCHEMBL7304356 | 0.85 | PDE3B (0.46) | LMNAMAPK1NPC1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |