Hydroxyamine

Hydroxyamine

SCHEMBL7320378

NO.O=C(N[C@H](C(=O)O)C(O)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)OCc1ccccc1

nearest known ligand 0.53

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.45
F10 P00742 2/20 0.45
PRSS1 P07477 2/20 0.45
PRSS2 P07478 2/20 0.45
F7 P08709 2/20 0.45
F3 P13726 2/20 0.45
PRSS3 P35030 2/20 0.45
CTSL P07711 3/20 0.44
CTSS P25774 3/20 0.44
CTSB P07858 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ACHE P22303 1/20 0.42
CTSK P43235 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyamine SCHEMBL7320373 1.00 F2 (0.45) F2F10PRSS1PRSS2F7
SCHEMBL2116716 0.98 CTSL (0.46) F2F10PRSS1PRSS2F7
SCHEMBL7311447 0.98 CTSL (0.46) F2F10PRSS1PRSS2F7
SCHEMBL10005610 0.98 CTSL (0.46) F2F10PRSS1PRSS2F7
SCHEMBL10039872 0.98 CTSL (0.46) F2F10PRSS1PRSS2F7
SCHEMBL7309373 0.98 CTSL (0.46) F2F10PRSS1PRSS2F7
SCHEMBL9501192 0.91 CTSL (0.46) CTSLCTSSCTSBCA1CA2
SCHEMBL10363640 0.89 TRPM8 (0.49) F2F10PRSS1PRSS2F7
SCHEMBL9501314 0.89 TRPM8 (0.49) F2F10PRSS1PRSS2F7
SCHEMBL7312947 0.88 CTSL (0.41) F2F10PRSS1PRSS2F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4319040-A Process for the production of optically active threo-3-(3,4-dihydroxyphenyl)serine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-03-09 US disclosed
EP-0024210-A1 Process for the production of optically active threo-3-(3,4-dihydroxyphenyl) serine, and product thus produced SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-02-25 EP disclosed