Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27444334 | 0.83 | GABBR2 (0.45) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL1666942 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL10424418 | 0.80 | GABBR2 (0.45) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL9818759 | 0.80 | GABBR2 (0.45) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL20640572 | 0.78 | GABBR2 (0.53) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| 3,3-Diphenylpropanoic Acid SCHEMBL20981393 | 0.76 | FFAR1 (0.59) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL9193585 | 0.75 | LMNA (0.38) | GABBR2GABBR1ADRA2AADRA2CLMNA | |
| SCHEMBL29999110 | 0.74 | DPP4 (0.52) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL6449839 | 0.74 | GABBR2 (0.48) | GABBR2GABBR1ADRA2CLMNACYP2C19 | |
| SCHEMBL17493151 | 0.73 | SLC22A6 (0.42) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |