Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320534 | 0.75 | GABBR2 (0.47) | LMNAALDH1A1GABBR2GABBR1CYP2C19 | |
| SCHEMBL16569135 | 0.75 | LMNA (0.45) | LMNAALDH1A1RENHIF1A | |
| SCHEMBL939400 | 0.75 | LMNA (0.45) | LMNAALDH1A1RENHIF1A | |
| SCHEMBL27444334 | 0.73 | GABBR2 (0.45) | LMNAALDH1A1GABBR2GABBR1CYP2C19 | |
| SCHEMBL31003034 | 0.72 | PSMB5 (0.48) | ALDH1A1ANPEPRENMAPTBACE1 | |
| SCHEMBL29885722 | 0.71 | CACNA2D1 (0.42) | ALDH1A1RNPEPCYP2C19 | |
| SCHEMBL31633387 | 0.71 | METAP2 (0.41) | MMP1MMP2MMP3MMP9ANPEP | |
| SCHEMBL609044 | 0.70 | KDM4E (0.36) | ALDH1A1ANPEPRENLAP3BACE1 | |
| SCHEMBL11909491 | 0.70 | CACNA2D1 (0.46) | LMNA | |
| 3-Methylbutanoic Acid SCHEMBL27920816 | 0.70 | GABBR2 (0.52) | LMNAALDH1A1GABBR2GABBR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409962-B1 | AGENT FOR INHIBITING HIV-PROTEASES | SCHRAMM WOLFGANG (DE) | 1995-12-06 | — | — | EP | claimed |