Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333102 | 0.94 | MAPT (0.48) | MAPTMAPK1KDM4ETSHRHSD17B10 | |
| SCHEMBL7321924 | 0.89 | SLC6A3 (0.47) | MAPTKDM4EESR1PTGDR2PRSS1 | |
| Bicarbonate SCHEMBL7333292 | 0.87 | SLC6A3 (0.46) | MAPTKDM4EESR1PTGDR2PRSS1 | |
| SCHEMBL9473309 | 0.85 | KDM4E (0.65) | MAPTMAPK1KDM4ETSHRHSD17B10 | |
| SCHEMBL7324828 | 0.84 | FTO (0.47) | MAPTALDH1A1LMNAPRSS1F2 | |
| SCHEMBL7331521 | 0.84 | PTGDR2 (0.43) | MAPTKDM4EELANEPTGDR2PRSS1 | |
| SCHEMBL7331841 | 0.84 | ESR1 (0.50) | MAPTMAPK1ALDH1A1ESR1GAA | |
| SCHEMBL7323625 | 0.83 | ALDH1A1 (0.52) | MAPTALDH1A1LMNAPRSS1F2 | |
| Bromide SCHEMBL7327444 | 0.83 | PTGDR2 (0.42) | MAPTKDM4EELANEPTGDR2PRSS1 | |
| Bromide SCHEMBL7330269 | 0.83 | ESR1 (0.49) | MAPTMAPK1ALDH1A1ESR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58041855-A | — | — | None | — | — | JP | disclosed |
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| JP-S5841855-A | AMIDINE COMPOUND | TORII YAKUHIN KK | 1983-03-11 | — | — | JP | disclosed |