Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315049 | 0.88 | L3MBTL1 (0.37) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL7311761 | 0.83 | PDE3B (0.36) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL10374990 | 0.82 | L3MBTL1 (0.41) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL7311792 | 0.81 | PDE3B (0.48) | PDE3BPDE3AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10377014 | 0.81 | SMN1; SMN2 (0.39) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL7303038 | 0.79 | PDE3B (0.36) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL10375053 | 0.79 | THRA (0.40) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL10374810 | 0.78 | PDE3B (0.45) | L3MBTL1PDE3BPDE3AMAPTKMT2A | |
| SCHEMBL10376587 | 0.78 | L3MBTL1 (0.39) | L3MBTL1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL10375748 | 0.78 | L3MBTL1 (0.41) | L3MBTL1MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |