Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311761 | 0.88 | PDE3B (0.36) | PDE3BPDE3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10374675 | 0.86 | PDE3B (0.39) | PDE3BPDE3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7315049 | 0.83 | L3MBTL1 (0.37) | PDE3BPDE3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7311484 | 0.81 | PDE3B (0.47) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7320618 | 0.79 | L3MBTL1 (0.37) | PDE3BPDE3ACYP2D6CYP2C19MEN1 | |
| SCHEMBL10374677 | 0.79 | PDE3B (0.39) | PDE3BPDE3AMEN1KMT2AL3MBTL1 | |
| SCHEMBL7320580 | 0.78 | PDE3B (0.40) | PDE3BPDE3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7303043 | 0.78 | CASP6 (0.35) | PDE3BPDE3APPARGL3MBTL1PDE4A | |
| SCHEMBL7314783 | 0.77 | CASP6 (0.35) | PDE3BPDE3ACYP2D6CYP2C19PPARG | |
| SCHEMBL7310962 | 0.75 | PDE3B (0.43) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |