SCHEMBL732071

SCHEMBL732071

C1CC(OCC2CO2)CC1OCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 8/20 0.39
TDP1 Q9NUW8 3/20 0.38
MAPK1 P28482 1/20 0.37
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730238 0.91 TSHR (0.43) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL733109 0.90 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7079859 0.90 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17085515 0.90 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23135367 0.89 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12292918 0.85 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1076015 0.83 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14415206 0.83 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14062955 0.83 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23135424 0.82 TSHR (0.36) TSHRSMN1; SMN2ALDH1A1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022263943-A1 TWO-PART CURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-22 WO disclosed
US-9624380-B2 Sulfide extended epoxy resins and barrier coating applications thereof SUN CHEMICAL CORPORATION (US) 2017-04-18 US disclosed
US-20140342091-A1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATING APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2014-11-20 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-8765984-B2 Methods and systems for making thiol compounds from terminal olefinic compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-07-01 US disclosed
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-09-13 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
US-7910666-B2 Mercaptan-hardened epoxy polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-03-22 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
WO-2009132010-A1 METHODS AND SYSTEMS FOR MAKING THIOL COMPOUNDS FROM TERMINAL OLEFINIC COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-29 WO disclosed
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-22 US disclosed
EP-1940992-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070112100-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-05-17 US disclosed
WO-2007022217-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885SMN1; SMN2 4271/4885ALDH1A1 157/4885
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885SMN1; SMN2 4271/4885ALDH1A1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.