Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.40 |
| ▸ | DRD1 | P21728 | 10/20 | 0.40 |
| ▸ | DRD4 | P21917 | 10/20 | 0.40 |
| ▸ | HTR2C | P28335 | 10/20 | 0.40 |
| ▸ | DRD3 | P35462 | 10/20 | 0.40 |
| ▸ | DRD5 | P21918 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326195 | 0.86 | SLC6A4 (0.52) | HTR2CSLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL7324686 | 0.78 | CNR2 (0.39) | SLC6A4SIGMAR1TMEM97EBP | |
| Hydrochloric Acid SCHEMBL7319927 | 0.78 | SIGMAR1 (0.54) | SLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL7322425 | 0.77 | SLC6A4 (0.41) | SLC6A4SIGMAR1TMEM97 | |
| SCHEMBL7319768 | 0.76 | SLC6A4 (0.45) | HTR2CSLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL7325407 | 0.76 | SLC6A4 (0.41) | SLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL7317938 | 0.74 | SIGMAR1 (0.39) | SLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL27467451 | 0.74 | SLC6A4 (0.38) | SLC6A4SIGMAR1TMEM97EBP | |
| SCHEMBL7325149 | 0.72 | SIGMAR1 (0.64) | SIGMAR1TMEM97EBP | |
| SCHEMBL7318910 | 0.72 | SIGMAR1 (0.64) | SIGMAR1TMEM97EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |