SCHEMBL7325407

SCHEMBL7325407

CCN(CC1CC1c1ccc(C2CCCCC2)c(Cl)c1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 7/20 0.41
SIGMAR1 Q99720 2/20 0.40
TMEM97 Q5BJF2 1/20 0.40
EBP Q15125 1/20 0.40
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
TAAR1 Q96RJ0 4/20 0.34
GRM2 Q14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7326195 0.84 SLC6A4 (0.52) SLC6A4SIGMAR1TMEM97EBPSLC6A2
SCHEMBL7319768 0.80 SLC6A4 (0.45) SLC6A4SIGMAR1TMEM97EBPSLC6A2
Hydrochloric Acid SCHEMBL7319927 0.80 SIGMAR1 (0.54) SLC6A4SIGMAR1TMEM97EBPSLC6A2
SCHEMBL7322425 0.79 SLC6A4 (0.41) SLC6A4SIGMAR1TMEM97SLC6A2SLC6A3
SCHEMBL27467451 0.78 SLC6A4 (0.38) SLC6A4SIGMAR1TMEM97EBPSLC6A2
SCHEMBL7317938 0.77 SIGMAR1 (0.39) SLC6A4SIGMAR1TMEM97EBPSLC6A2
SCHEMBL27466552 0.76 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3TAAR1GRM2
SCHEMBL7320711 0.76 DRD2 (0.40) SLC6A4SIGMAR1TMEM97EBP
SCHEMBL7321171 0.76 GPR88 (0.44)
SCHEMBL8329993 0.74 FFAR4 (0.37) SLC6A4SIGMAR1TMEM97SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1154483-C Use of amines to produce drugs for preventing tumour cell proliferation ��ŵ��-ʥ�������ɷ����޹�˾ 2004-06-23 CN disclosed
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN disclosed
EP-0917464-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1999-05-26 EP disclosed
WO-1998004251-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1998-02-05 WO disclosed