Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319768 | 0.89 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL8329993 | 0.81 | FFAR4 (0.37) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL7315921 | 0.79 | APP (0.41) | SLC6A4SLC6A3OPRM1OPRD1OPRK1 | |
| SCHEMBL7325407 | 0.79 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL7326195 | 0.78 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL27467452 | 0.78 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL7326207 | 0.77 | SIGMAR1 (0.48) | SIGMAR1SLC18A3 | |
| SCHEMBL7320711 | 0.77 | DRD2 (0.40) | SLC6A4SIGMAR1TMEM97 | |
| SCHEMBL27467451 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL7326142 | 0.75 | CCR5 (0.47) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |