Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23105099 | 0.86 | ARG1 (0.40) | ARG1ARG2CHRM4LMNA | |
| SCHEMBL12308359 | 0.85 | SLC18A3 (0.39) | SIGMAR1TACR2ARG1ARG2CHRM4 | |
| SCHEMBL1381371 | 0.85 | GBA1 (0.40) | SIGMAR1TACR2ARG1ARG2CHRM4 | |
| SCHEMBL23946081 | 0.83 | ARG1 (0.41) | ARG1ARG2CHRM4HRH3GBA1 | |
| SCHEMBL3865451 | 0.81 | PIK3CD (0.41) | CHRM4ACHEHRH3 | |
| SCHEMBL23105149 | 0.80 | GNAO1 (0.47) | ARG1ARG2CHRM4HRH3MAPT | |
| SCHEMBL1318049 | 0.80 | SLC18A3 (0.46) | CHRM4ACHEHRH3BRD4LMNA | |
| SCHEMBL25877203 | 0.79 | ARG1 (0.41) | SIGMAR1ARG1ARG2CHRM4 | |
| SCHEMBL22824641 | 0.79 | NOS3 (0.36) | SIGMAR1TACR2ARG1ARG2CHRM4 | |
| SCHEMBL10052292 | 0.79 | ARG1 (0.37) | SIGMAR1ARG1ARG2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |