Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307614 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1MAPTTDP1GAA | |
| SCHEMBL7311430 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1MAPTTDP1GAA | |
| SCHEMBL10377209 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1MAPTTDP1GAA | |
| SCHEMBL7320743 | 0.74 | MAOB (0.38) | MAOBKDM4EALDH1A1MAOA | |
| SCHEMBL7320749 | 0.73 | MAOB (0.39) | MAOBKDM4EMAOA | |
| SCHEMBL7320282 | 0.69 | PDE3B (0.53) | — | |
| SCHEMBL7317560 | 0.68 | PDE3B (0.56) | — | |
| SCHEMBL12897966 | 0.68 | MAPT (0.57) | KDM4EALDH1A1MAPTTDP1GAA | |
| SCHEMBL7318453 | 0.67 | KDM4E (0.46) | MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL7307151 | 0.66 | KDM4E (0.47) | MAOBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |