Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311419 | 0.87 | ALDH1A1 (0.35) | ALDH1A1RECQLKDM4ELMNA | |
| SCHEMBL7307607 | 0.86 | LMNA (0.36) | ALDH1A1RECQLKDM4ELMNA | |
| SCHEMBL7320749 | 0.84 | MAOB (0.39) | MAOBTHRBKDM4EMAOALMNA | |
| SCHEMBL10377206 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNA | |
| SCHEMBL7320758 | 0.74 | MAOB (0.39) | MAOBALDH1A1KDM4EMAOA | |
| SCHEMBL7311424 | 0.71 | LMNA (0.37) | ALDH1A1KDM4ELMNA | |
| SCHEMBL7307610 | 0.71 | SIRT3 (0.38) | ALDH1A1KDM4ELMNA | |
| SCHEMBL7309450 | 0.70 | MAPT (0.52) | ALDH1A1THRBKDM4ELMNA | |
| SCHEMBL7317546 | 0.69 | PDE3B (0.56) | — | |
| SCHEMBL7318455 | 0.69 | KDM4E (0.47) | MAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |