Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320758 | 0.87 | MAOB (0.39) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL10377209 | 0.86 | KDM4E (0.39) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7307614 | 0.86 | KDM4E (0.37) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7311419 | 0.74 | ALDH1A1 (0.35) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7311424 | 0.73 | LMNA (0.37) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL11113955 | 0.72 | KDM4E (0.35) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7318161 | 0.71 | ALB (0.47) | MAPTTDP1MEN1KMT2APDE3B | |
| SCHEMBL14294184 | 0.70 | MAPT (0.54) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7311375 | 0.70 | ALB (0.46) | MAPTTDP1MEN1KMT2APDE3B | |
| SCHEMBL7311369 | 0.70 | MAPT (0.39) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |