Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320758 | 0.87 | MAOB (0.39) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7311430 | 0.86 | KDM4E (0.37) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL10377209 | 0.78 | KDM4E (0.39) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7307607 | 0.75 | LMNA (0.36) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7307610 | 0.75 | SIRT3 (0.38) | KDM4EMAPTALDH1A1TDP1GAA | |
| SCHEMBL7320282 | 0.68 | PDE3B (0.53) | — | |
| SCHEMBL7318298 | 0.67 | KDM4E (0.45) | KDM4EMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL7317560 | 0.67 | PDE3B (0.56) | — | |
| SCHEMBL7314547 | 0.67 | KDM4E (0.46) | KDM4EMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL7317244 | 0.66 | PDE3B (0.41) | KDM4EMAPTALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |