Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399205 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| Hydrochloric Acid SCHEMBL11630508 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| SCHEMBL394063 | 0.83 | NQO2 (0.46) | ALDH1A1LMNAHPGDMAPTSMN1; SMN2 | |
| SCHEMBL7352212 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| SCHEMBL3504817 | 0.81 | NQO2 (0.49) | ALDH1A1LMNAHPGDPTPN1KDM4E | |
| SCHEMBL11627043 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| Hydrochloric Acid SCHEMBL7318890 | 0.75 | CACNA1G (0.51) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| SCHEMBL9480386 | 0.74 | SLC9A1 (0.58) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| SCHEMBL11826852 | 0.74 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDERCC5FEN1 | |
| SCHEMBL26486695 | 0.73 | PTPN1 (0.47) | ALDH1A1LMNAHPGDERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882354-A | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0321431-A1 | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |