Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | PKLR | P30613 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789908 | 0.89 | HIF1A (0.62) | PKMPKLRHIF1ASMN1; SMN2MEN1 | |
| SCHEMBL7791354 | 0.85 | PLAU (0.72) | PKMPKLRHIF1ASMN1; SMN2MEN1 | |
| SCHEMBL7322058 | 0.84 | MEN1 (0.75) | PKMPKLRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7319886 | 0.83 | LMNA (0.69) | PKMPKLRHIF1ASMN1; SMN2MEN1 | |
| SCHEMBL1883726 | 0.81 | MEN1 (0.64) | PKMPKLRHIF1ASMN1; SMN2MEN1 | |
| SCHEMBL27939522 | 0.79 | HIF1A (0.55) | HIF1ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5377032 | 0.79 | PLAU (0.70) | PKMPKLRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30709099 | 0.78 | HIF1A (0.96) | HIF1ASMN1; SMN2LMNA | |
| SCHEMBL26603234 | 0.78 | HIF1A (0.96) | HIF1ASMN1; SMN2LMNA | |
| SCHEMBL2824645 | 0.78 | AR (0.67) | HIF1ASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |