SCHEMBL7791354

SCHEMBL7791354

CCOC(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 3/20 0.72
SMN1; SMN2 Q16637 5/20 0.69
ALDH1A1 P00352 3/20 0.69
LMNA P02545 3/20 0.69
GAA P10253 1/20 0.69
NHERF1 O14745 1/20 0.66
HIF1A Q16665 1/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
HPGD P15428 3/20 0.64
ALOX15 P16050 1/20 0.64
MAPK1 P28482 1/20 0.64
HSD17B10 Q99714 1/20 0.64
MAPT P10636 1/20 0.63
TSHR P16473 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
HDAC3 O15379 1/20 0.63
HDAC4 P56524 1/20 0.63
HDAC1 Q13547 1/20 0.63
HDAC7 Q8WUI4 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319886 0.88 LMNA (0.69) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL2824645 0.88 AR (0.67) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL7320847 0.85 PKM (0.64) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL7782225 0.84 NHERF1 (0.76) SMN1; SMN2ALDH1A1LMNAGAANHERF1
SCHEMBL7789908 0.83 HIF1A (0.62) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL13028451 0.82 NHERF1 (0.73) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL10420649 0.82 NHERF1 (0.80) SMN1; SMN2ALDH1A1LMNAGAANHERF1
SCHEMBL8275407 0.82 ALDH1A1 (1.00) PLAUSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL31615314 0.81 MEN1 (0.71) SMN1; SMN2ALDH1A1LMNANHERF1MEN1
SCHEMBL1883726 0.81 MEN1 (0.64) PLAUSMN1; SMN2ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251917-B1 Benzamidoaldehydes and their use as cysteine protease inhibitors BASF AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed