SCHEMBL732095

SCHEMBL732095

COC(=O)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.58
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
MAPT P10636 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TTR P02766 1/20 0.48
PPOX P50336 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
KCNH2 Q12809 1/20 0.46
MAPK1 P28482 2/20 0.45
MRGPRX4 Q96LA9 2/20 0.43
SCN8A Q9UQD0 1/20 0.43
SCN10A Q9Y5Y9 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11258317 0.92 FFAR1 (0.54) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL941173 0.91 FFAR1 (0.51) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL147772 0.91 FFAR1 (0.51) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL29382403 0.91 FFAR1 (0.51) FFAR1MEN1KMT2AMAPTL3MBTL1
Diclofop-Methyl SCHEMBL10670222 0.91 FFAR1 (0.48) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL8749233 0.91 FFAR1 (0.50) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL8749252 0.91 FFAR1 (0.50) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL11442480 0.90 FFAR1 (0.52) FFAR1MEN1KMT2AMAPTL3MBTL1
SCHEMBL8749291 0.90 FFAR1 (0.49) FFAR1MEN1KMT2AMAPTTTR
SCHEMBL10963334 0.88 FFAR1 (0.58) FFAR1MEN1KMT2AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330904-B1 Herbicidal agent in the form of aqueous microemulsions HOECHST AG (DE) 1994-04-20 EP claimed
US-4973352-A Herbicidal agents in the form of aqueous transparent microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-27 US claimed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-1893016-B1 WATER-IN-OIL SUSPOEMULSIONS BAYER IP GMBH (DE) 2017-09-13 EP disclosed
EP-1651039-B1 OIL SUSPENSION CONCENTRATE CONTAINING DIFLUFENICAN BAYER IP GMBH (DE) 2017-01-04 EP disclosed
EP-1928232-B1 SOLID FORMULATION BAYER IP GMBH (DE) 2016-07-13 EP disclosed
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2015-09-03 US disclosed
EP-2908639-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES Bayer Cropscience AG (DE) 2015-08-26 EP disclosed
US-9102623-B2 Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use BAYER CROPSCIENCE AG (DE) 2015-08-11 US disclosed
EP-2144879-B1 PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION BAYER IP GMBH (DE) 2015-04-08 EP disclosed
EP-1571908-B1 OIL SUSPENSION CONCENTRATE BAYER CROPSCIENCE AG (DE) 2014-12-17 EP disclosed
US-4466822-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
US-4451286-A PLANT SAFENING CIBA-GEIGY CORPORATION (US) 1984-05-29 US disclosed
US-4415743-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS; ANTIDOTES CIBA-GEIGY CORPORATION (US) 1983-11-15 US disclosed
US-4414020-A AMIDOXIMES AS SAFENING AGENTS HOECHST AG (DE) 1983-11-08 US disclosed
US-4335249-A PREEMERGENCE AND POSTEMERGENCE ROHM AND HAAS COMPANY (US) 1982-06-15 US disclosed
EP-0002800-B1 Optically active alpha-phenoxypropionic acid dervatives HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed
US-4252980-A Process for the manufacture of (phenoxy or benzyl)-phenoxypropionic acid methyl esters HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4220464-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as plant growth regulator CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4070178-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES AADAC, PFAS, CBR3 FFAR1 546/4885MEN1 4245/4885KMT2A 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.