SCHEMBL941173

SCHEMBL941173

COC(=O)C(C)Oc1ccc2ccc(Oc3ccc(C(F)(F)F)cc3Cl)cc2c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.51
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TTR P02766 1/20 0.47
PPOX P50336 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTR2A P28223 2/20 0.46
SLC6A4 P31645 2/20 0.46
KCNH2 Q12809 2/20 0.46
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MRGPRX4 Q96LA9 2/20 0.41
SCN8A Q9UQD0 1/20 0.41
SCN10A Q9Y5Y9 1/20 0.41
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382403 1.00 FFAR1 (0.51) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL147772 1.00 FFAR1 (0.51) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL732095 0.91 FFAR1 (0.58) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL10645967 0.90 FFAR1 (0.50) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL10648299 0.90 FFAR1 (0.46) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL11258317 0.90 FFAR1 (0.54) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL9633459 0.89 FFAR1 (0.52) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL10646108 0.89 FFAR1 (0.52) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL10643884 0.89 FFAR1 (0.52) FFAR1MEN1KMT2ATTRPPOX
SCHEMBL10644204 0.89 FFAR1 (0.52) FFAR1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179015-B1 7-(ARYLOXY)-2-NAPHTHOXYALKANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION OF THESE COMPOUNDS, AS WELL AS AGENTS HAVING HERBICIDAL ACTIVITY CONTAINING THESE COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1988-04-13 EP claimed
US-4709077-A 7-(aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1987-11-24 US claimed
EP-0179015-A1 7-(Aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1986-04-23 EP claimed
CN-118201483-A ALS inhibitor herbicide tolerant beet (Beta Vulgaris) mutants 科沃施种子欧洲股份两合公司 2024-06-14 CN disclosed
US-20190133118-A1 TIME-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME BAYER CROPSCIENCE AKTIENGESSELSCHAFT (DE) 2019-05-09 US disclosed
WO-2017186577-A1 TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME BAYER CROPSCIENCE AKTIENGESSELSCHAFT (DE) 2017-11-02 WO disclosed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-2967063-B1 LAWN GROWTH-PROMOTING AGENT AND METHOD OF USING SAME BAYER CROPSCIENCE AG (DE) 2017-10-18 EP disclosed
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2015-09-03 US disclosed
EP-2908639-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES Bayer Cropscience AG (DE) 2015-08-26 EP disclosed
US-9102623-B2 Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use BAYER CROPSCIENCE AG (DE) 2015-08-11 US disclosed
US-20100048400-A1 HERBICIDE COMBINATION BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
US-20080305953-A1 Liquid Formulations Containing Dialkyl Sulfosuccinate And Hydroxyphenylpyruvate Dioxygenase Inhibitors BAYER CROPSCIENCE AG (DE) 2008-12-11 US disclosed
US-20080269059-A1 PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE BAYER CROPSCIENCE AG (DE) 2008-10-30 US disclosed
US-20080269052-A1 USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS BAYER CROPSCIENCE AG (DE) 2008-10-30 US disclosed
US-20070054806-A1 Novel sulfonamide-comprising solid formulations BAYER CROPSCIENCE GMBH (DE) 2007-03-08 US disclosed
US-20070054805-A1 Novel sulfonamide-comprising solid formulations BAYER CROPSCIENCE GMBH (DE) 2007-03-08 US disclosed
US-20070054807-A1 Storage-stable formulations of sulfonamides BAYER CROPSCIENCE GMBH (DE) 2007-03-08 US disclosed
US-20050032647-A1 Mixture of herbically active material, solvent and sulfosuccinic acid compound BAYER CROPSCIENCE GMBH (DE) 2005-02-10 US disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269052-A1 USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS CBR3, CBR1, CYP4Z1 FFAR1 1478/4885MEN1 4633/4885KMT2A 2070/4885
US-20070054806-A1 Novel sulfonamide-comprising solid formulations SULT2A1, ARSA, SLC43A1 FFAR1 2305/4885MEN1 4851/4885KMT2A 453/4885
US-20190133118-A1 TIME-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME SLC18A1, GRN, SAMM50 FFAR1 3215/4885MEN1 2196/4885KMT2A 4175/4885
US-20080305953-A1 Liquid Formulations Containing Dialkyl Sulfosuccinate And Hydroxyphenylpyruvate Dioxygenase Inhibitors HPD, DDT, HAAO FFAR1 1225/4885MEN1 4768/4885KMT2A 1850/4885
US-20080269059-A1 PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE CYC1, PYCR1, CBR3 FFAR1 3759/4885MEN1 2387/4885KMT2A 1799/4885
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES AADAC, PFAS, CBR3 FFAR1 546/4885MEN1 4245/4885KMT2A 720/4885
US-20100048400-A1 HERBICIDE COMBINATION DDT, DRD1, DRD2 FFAR1 570/4885MEN1 4845/4885KMT2A 3756/4885
US-20050032647-A1 Mixture of herbically active material, solvent and sulfosuccinic acid compound STS, SCLY, SRM FFAR1 600/4885MEN1 4238/4885KMT2A 900/4885
US-20070054805-A1 Novel sulfonamide-comprising solid formulations SULT2A1, ARSA, SLC43A1 FFAR1 2558/4885MEN1 4818/4885KMT2A 581/4885
US-20070054807-A1 Storage-stable formulations of sulfonamides STS, ARSA, SMS FFAR1 1976/4885MEN1 4042/4885KMT2A 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.