Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 4/20 | 0.44 |
| ▸ | PLAT | P00750 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7325582 | 0.99 | PLAU (0.44) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7330969 | 0.95 | FTO (0.42) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL11217581 | 0.95 | FTO (0.42) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7323625 | 0.91 | ALDH1A1 (0.52) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7321924 | 0.90 | SLC6A3 (0.47) | F2PRSS1KMT2AMAPTSLC6A3 | |
| Bicarbonate SCHEMBL7333292 | 0.89 | SLC6A3 (0.46) | F2PRSS1KMT2AMAPTSLC6A3 | |
| SCHEMBL7323125 | 0.87 | ALDH1A1 (0.48) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7324828 | 0.86 | FTO (0.47) | F2PRSS1KLKB1KLK1KMT2A | |
| SCHEMBL7331841 | 0.85 | ESR1 (0.50) | KMT2AMAPTLMNAGFERSLC6A3 | |
| Bromide SCHEMBL7330269 | 0.84 | ESR1 (0.49) | KMT2AMAPTLMNAGFERSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | claimed |
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |